Document Details

Document Type : Thesis 
Document Title :
Effect of Thyroid Hormones Disorder on Lipids profile in Adult Human
تأثير اختلال هرمونات الغدة الدرقية على مستوى الشحميات في الإنسان البالغ
 
Subject : Thyroid gland--Diseases 
Document Language : English 
Abstract : The hormones of the thyroid gland regulate the metabolism of lipids in every cell of the body. Thyroid disorders occur when the thyroid gland produces less (hypothyroid) or more (hyperthyroid) thyroid hormones than the body needs. Thyroid function disorders lead to changes in lipid levels of blood, total Cholesterol, LDL-cholesterol, HDL-cholesterol and triacylglycerols which are considered to be important risk factors for atherosclerosis. The aim of the present study was designed to find out any possible relationship between thyroid hormones disorders (hypothyroid or hyperthyroid) and lipid profile. In order to realize the aim and target of this study the following steps were followed. A total of 203 male and female volunteer subjects (51 males and 152 females) with age range of 20-60 years. These were divided into two groups: normal control subjects and subjects with thyroid hormones disorder (hypothyroidism or hyperthyroidism). It was found that the plasma concentrations of total Cholesterol, LDL-C, triacylglycerols and glucose were significantly increased by approximately 24.29%, 24.56%, 31.82% and 31.84% in hypothyroid females as compared to normal controls. The plasma concentration of triacylglycerols was significantly increased by 48.49% while the plasma concentration of HDL-C was significantly decreased by 19.56% in hypothyroid males as compared to normal controls. The present study indicated that there was a significant negative correlation between FT3 and each of total and LDL-C of hypothyroid males. While there was a significant positive correlation between TSH and triacylglycerols of hyperthyroid male and female subjects. One may conclude that hypothyroidism is associated with hyperlipidemia , while hyperthyroid did not affect lipid levels. PDF created 
Supervisor : Samir Muhammad Khoja 
Thesis Type : Master Thesis 
Publishing Year : 1431 AH
2010 AD 
Added Date : Tuesday, December 2, 2014 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سحر عبد الرحمن الخضيرAl-khodair, Sahar AbdulrahmanInvestigatorMaster 

Files

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 37593.pdf pdf 

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